We are cell biologists applying engineering methods to discover new mechanisms operating at cell-cell and cell-extracellular matrix adhesions that instruct tissue morphogenesis. 

Ultimately, we are interested in uncovering fundamental molecular and mechanical mechanisms that conspire across time and length scales to organize and shape human tissues. To do so, we develop microfluidic, biomimetic human tissue models that recapitulate 3D in vivo architectures, microenvironments, cellular heterogeneity, and morphogenic behaviors that can be examined mechanistically by biochemical and cell biological approaches. Combined with advanced microscopy, cellular and molecular engineering, and 'omic' technologies, our multidisciplinary approach allows us to model, control, and dissect complex multicellular behaviors at a level previously only accessible in vivo. ​

The Kutys Lab resides within the Department of Cell and Tissue Biology at the University of California San Francisco Parnassus Campus. We are members of the Helen Diller Family Comprehensive Cancer Center and Cardiovascular Research Institutes. 

Our lab is generously supported by:

Recent Lab News:

2024/01
Congratulations to Lakyn Mayo on her NHLBI F31 predoctoral fellowship!

2024/01
Congratulations to incoming postdoc Iris Liu on her AHA postdoctoral fellowship!

2023/12
NEW GRANT
The Kutys and Ernst Labs are award a R21 from the NIAID to develop and apply biomimetic human TB granuloma models!

​We are hiring postdoctoral fellows!​

2023/10
NEW PAPER
Check out Matthew's new paper at JCB on how Notch signaling can directly influence epithelial mechanics and adhesion!​

Check the News page for more lab news!