We are cell biologists applying engineering methods to discover new mechanisms operating at cell-cell and cell-extracellular matrix adhesions that instruct tissue morphogenesis. 

Ultimately, we are interested in uncovering fundamental molecular and mechanical mechanisms that conspire across time and length scales to organize and shape human tissues. To do so, we develop microfluidic, biomimetic human tissue models that recapitulate 3D in vivo architectures, microenvironments, cellular heterogeneity, and morphogenic behaviors that can be examined mechanistically by biochemical and cell biological approaches. Combined with advanced microscopy, cellular and molecular engineering, and 'omic' technologies, our multidisciplinary approach allows us to model, control, and dissect complex multicellular behaviors at a level previously only accessible in vivo. ​

The Kutys Lab resides within the Department of Cell and Tissue Biology at the University of California San Francisco Parnassus Campus. We are members of the Helen Diller Family Comprehensive Cancer Center and Cardiovascular Research Institutes. 

Our lab is generously supported by:

Recent Lab News:

2023/10
NEW PAPER
Check out Matthew's new paper at JCB on how Notch signaling can directly influence epithelial mechanics and adhesion!​

2023/10
NEW PAPER
Check out Matthew and Tania's JCS review/perspective on using microphysiological systems to model tissue morphogenesis!​

2023/010
Anand Verma joins the lab as a research specialist.




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2023/010
We are RECRUITING!

The Kutys and Ernst Labs are actively recruiting a postdoctoral fellow. See the Join! tab for position details. 



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Check the News page for more lab news!