KUTYS LAB @ UCSF
  • Home
  • Team
  • Research
  • Publications
  • Join!
  • Contact
  • Lab News
  • Home
  • Team
  • Research
  • Publications
  • Join!
  • Contact
  • Lab News

Publications

 Google Scholar NCBI Bibliography

Preprints

Notch1 cortical signaling regulates epithelial architecture and cell-cell adhesion
Matthew J. White, Kyle A. Jacobs, Tania Singh, and Matthew L. Kutys
bioRxiv. 
Arp2/3 Complex Activity Enables Nuclear YAP for Naive Pluripotency of Human Embryonic Stem Cells
Nathaniel P. Meyer, Tania Singh, Matthew L. Kutys, Todd Nystul, and Diane L. Barber
bioRxiv. 
Microphysiological vascular malformation model reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation
Wen Yih Aw, Crescentia Cho, Hao Wang, Anne Hope Cooper, Elizabeth L. Doherty, David Rocco, Stephanie A. Huang, Sarah Kubik, Chloe P. Whitworth, Ryan Armstrong, Anthony J. Hickey, Boyce Griffith, Matthew L. Kutys, Julie Blatt, William J. Polacheck.
bioRxiv. Accepted at Science Advances.

Pubs

Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling
Minsuk K, Kaden M. Southard, Woon Ryoung K, Nam Hyeong K, Ramu G, Minji A, Hyun LJ, Min KK, Seo Hyun C, Farlow J, Georgakopoulos A, Robakis NK, Kutys ML, Daeha S, Hyeong Bum Kim, Yong Ho Kim, Jinwoo C, Gartner ZJ, Young-wook J. 
Nature Cell Biology (2022) [PDF] 
Conversation before crossing: dissecting metastatic tumor-vascular interactions in microphysiological systems
Mayo LN and Kutys ML
AJP Cell Physiology (2022) [PDF] ​
35 challenges in materials science being tackled by PIs under 35(ish) in 2021
B. Aguado, L. Bray, S. Caneva, J.-P. Correa-Baena, G. Di Martino, C. Fang, Y. Fang, P. Gehring, G. Grosso, X. Gu, P. Guo, Y. He, T. J. Kempa, M. Kutys, J. Li, T. Li, B. Liao, F. Liu, F. Molina-Lopez, A. Pickel, A. M. Porras, R. Raman, E. M. Sletten, Q. Smith, C. Tan, H. Wang, H. Wang, S. Wang, Z. Wang, G. Wehmeyer, L. Wei, Y. Yang, L. D. Zarzar, M. Zhao, Y. Zheng, S. Cranford.
Matter (2021) 4, 3804–3810. [PDF] 
3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain
​Doyle AD, Sykora DJ, Pacheco GG, Kutys ML, Yamada KM.
Developmental Cell (2021) 56,6:826-841.E4. [PDF] 
Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic, vascularized mammary duct platform 
​Kutys ML*, Polacheck WJ*, Welch MK, Gagnon KA, Kim S, Li L, Koorman T, McClatchey AI, Chen CS.
Nature Communications. (2020) 11:3377. [PDF] (*Equal contribution)
Microfabricated blood vessels for modeling the vascular transport barrier
Polacheck WJ, Kutys ML, Tefft JB, Chen CS.
Nature Protocols ​(2019) 14:1425-1454.​
[PDF]
  • Feature image on issue cover. 
Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration
Wang W, Pearson A, Kutys ML, Choi CK, Wozniak M, Baker BM, Chen CS.​
APL Bioengineering ​(2018) 2:046107.
 [PDF]
Force generation via β-cardiac myosin, titin, and α-actinin drives cardiac sarcomere assembly from focal adhesions
Chopra A*, Kutys ML*, Zhang K, Polacheck WJ, Sheng C, Eyckmans J, Seidman JG, Seidman CE, Hinson JT, Chen CS. 
Developmental Cell (2018) ​44(1):87-96. 
​​[PDF] (*Equal contribution)
  • ​​Allen Institute for Cell Science Short Cell Shorts: ​Video Highlight
A non-canonical Notch signaling complex regulates adherens junctions and endothelial barrier function
Polacheck WJ*, Kutys ML*, Yang J, Eyckmans JE, Wu Y, Vasavada H, Hirschi KK, and Chen CS.
Nature ​(2017) 552:258-262. [PDF] (*Equal contribution)
  • ​​Perspectives and Press: ​Current Biology Perspective, Trends in  Cell Biology Perspective , Science Signaling Highlight, ​​​Wyss Institute Press Release and Faculty of 1000 Highlights.
Forces and mechanotransduction in 3D vascular biology
Kutys ML and Chen CS.
Current Opinion in Cell Biology (2016) 42:73-79​. ​[PDF]
Rho GEFs and GAPs: emerging integrators of extracellular matrix signaling
Kutys ML and Yamada KM.​
Small GTPases (2015) 6(1):16-9. 
[PDF]
An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration
Kutys ML and Yamada KM.
Nature Cell Biology (2014) 16(9):909-17. [PDF]
  • ​​Highlights in Faculty of 1000.
 Regulation of cell adhesion and migration by cell-derived matrices 
Kutys ML, Doyle AD, Yamada KM.
Experimental Cell Research (2013) 319(16):2434-9.​ ​
[PDF]
Dimensions in cell migration
Doyle AD, Petrie RJ, Kutys ML, Yamada KM.
Current Opinion in Cell Biology (2013) 25(5):642-9. [PDF]
Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration
Li X, Zhou Q, Sunkara M, Kutys ML, Wu Z, Rychahou P, Morris AJ, Zhu H, Evers BM, Huang C.
Journal of Cell Science (2013) 126(12):2617-28.
 [PDF]
Micro-environmental control of cell migration--myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics
Doyle AD, Kutys ML, Conti MA, Matsumoto K, Adelstein RS, Yamada KM.
Journal of Cell Science (2012) 125(9):2244-56. [PDF]
  • ​​Highlight in Faculty of 1000.
Monte carlo analysis of neck linker extension in kinesin molecular motors
Kutys ML, Fricks J, Hancock WO.
PLoS Computational Biology (2010) 6(11):e1000980.
 [PDF]
Kutys Lab
Department of Cell and Tissue Biology
Helen Diller Family Comprehensive Cancer Center
Cardiovascular Research Institute
​
​513 Parnassus Ave
HSW 618
San Francisco, CA 94143
Picture
Last updated 01/2023
​​Copyright © Kutys Laboratory 2023, San Francisco, CA