PublicationsGoogle Scholar NCBI Bibliography |
PreprintsArp2/3 Complex Activity Enables Nuclear YAP for Naive Pluripotency of Human Embryonic Stem Cells
Nathaniel P. Meyer, Tania Singh, Matthew L. Kutys, Todd Nystul, and Diane L. Barber bioRxiv. PubsNotch1 cortical signaling regulates epithelial architecture and cell-cell adhesion
White MJ, Jacobs KA, Singh T, Mayo LN, Lin A, Chen CS, Jun YW, and Kutys ML. Journal of Cell Biology (2023). ‘Chip’-ing away at morphogenesis – application of organ-on-chip technologies to study tissue morphogenesis
White MJ, Singh T, Wang E, Smith Q, and Kutys ML. Journal of Cell Science (2023). A 3D biomimetic model of lymphatics reveals cell–cell junction tightening and lymphedema via a cytokine-induced ROCK2/JAM-A complex
Lee E, Chan SL, Lee Y, Kwak S, Wen A, Nguyen DT, Kutys ML, Alimperti S, Kolaryzk AM, Kwak TJ, Eyckmans JE, Bielenberg DR, Chen H, Chen CS. PNAS (2023). A convolutional neural network STIFMap reveals associations between stromal stiffness and EMT in breast cancer
Stashko C, Hayward MK, Northey JJ, Pearson N, Ironside AJ, Lakins JN, Oria R, Goyette MA, Mayo L, Russnes HG, Hwang ES, Kutys ML, Polyak K, Weaver VM. Nature Communications (2023) [PDF] Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation
Adler FR, Anderson ARA, Bhushan A, Bogdan P, Bravo-Cordero JJ, Brock A, Chen Y, Cukierman E, DelGiorno KE, Denis GV, Ferrall-Fairbanks MC, Gartner ZJ, Germain RN, Gordon DM, Hunter G, Jolly MK, Karacosta LG, Mythreye K, Katira P, Kulkarni RP, Kutys ML, Lander AD, Laughney AM, Levine H, Lou E, Lowenstein PR, Masters KS, Pe'er D, Peyton SR, Platt MO, Purvis JE, Quon G, Richer JK, Riddle NC, Rodriguez A, Snyder JC, Lee Szeto G, Tomlin CJ, Yanai I, Zervantonakis IK, Dueck H. Cell Systems (2023) [PDF] Microphysiological vascular malformation model reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation
Wen Yih Aw, Crescentia Cho, Hao Wang, Anne Hope Cooper, Elizabeth L. Doherty, David Rocco, Stephanie A. Huang, Sarah Kubik, Chloe P. Whitworth, Ryan Armstrong, Anthony J. Hickey, Boyce Griffith, Matthew L. Kutys, Julie Blatt, William J. Polacheck. Science Advances (2023) [PDF] Adherens junctions organize size-selective proteolytic hotspots critical for Notch signalling
Minsuk K, Kaden M. Southard, Woon Ryoung K, Nam Hyeong K, Ramu G, Minji A, Hyun LJ, Min KK, Seo Hyun C, Farlow J, Georgakopoulos A, Robakis NK, Kutys ML, Daeha S, Hyeong Bum Kim, Yong Ho Kim, Jinwoo C, Gartner ZJ, Young-wook J. Nature Cell Biology (2022) [PDF] Conversation before crossing: dissecting metastatic tumor-vascular interactions in microphysiological systems
Mayo LN and Kutys ML. AJP Cell Physiology (2022) [PDF] 35 challenges in materials science being tackled by PIs under 35(ish) in 2021
B. Aguado, L. Bray, S. Caneva, J.-P. Correa-Baena, G. Di Martino, C. Fang, Y. Fang, P. Gehring, G. Grosso, X. Gu, P. Guo, Y. He, T. J. Kempa, Kutys ML, J. Li, T. Li, B. Liao, F. Liu, F. Molina-Lopez, A. Pickel, A. M. Porras, R. Raman, E. M. Sletten, Q. Smith, C. Tan, H. Wang, H. Wang, S. Wang, Z. Wang, G. Wehmeyer, L. Wei, Y. Yang, L. D. Zarzar, M. Zhao, Y. Zheng, S. Cranford. Matter (2021) 4, 3804–3810. [PDF] 3D mesenchymal cell migration is driven by anterior cellular contraction that generates an extracellular matrix prestrain
Doyle AD, Sykora DJ, Pacheco GG, Kutys ML, Yamada KM. Developmental Cell (2021) 56,6:826-841.E4. [PDF] Uncovering mutation-specific morphogenic phenotypes and paracrine-mediated vessel dysfunction in a biomimetic, vascularized mammary duct platform
Kutys ML*, Polacheck WJ*, Welch MK, Gagnon KA, Kim S, Li L, Koorman T, McClatchey AI, Chen CS. Nature Communications. (2020) 11:3377. [PDF] (*Equal contribution) |
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Microfabricated blood vessels for modeling the vascular transport barrier
Polacheck WJ, Kutys ML, Tefft JB, Chen CS. Nature Protocols (2019) 14:1425-1454. [PDF]
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Extracellular matrix alignment dictates the organization of focal adhesions and directs uniaxial cell migration
Wang W, Pearson A, Kutys ML, Choi CK, Wozniak M, Baker BM, Chen CS. APL Bioengineering (2018) 2:046107. [PDF] |
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Force generation via β-cardiac myosin, titin, and α-actinin drives cardiac sarcomere assembly from focal adhesions
Chopra A*, Kutys ML*, Zhang K, Polacheck WJ, Sheng C, Eyckmans J, Seidman JG, Seidman CE, Hinson JT, Chen CS. Developmental Cell (2018) 44(1):87-96. [PDF] (*Equal contribution)
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A non-canonical Notch signaling complex regulates adherens junctions and endothelial barrier function
Polacheck WJ*, Kutys ML*, Yang J, Eyckmans JE, Wu Y, Vasavada H, Hirschi KK, and Chen CS. Nature (2017) 552:258-262. [PDF] (*Equal contribution)
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Forces and mechanotransduction in 3D vascular biology
Kutys ML and Chen CS. Current Opinion in Cell Biology (2016) 42:73-79. [PDF] |
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Rho GEFs and GAPs: emerging integrators of extracellular matrix signaling
Kutys ML and Yamada KM. Small GTPases (2015) 6(1):16-9. [PDF] |
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An extracellular-matrix-specific GEF-GAP interaction regulates Rho GTPase crosstalk for 3D collagen migration
Kutys ML and Yamada KM. Nature Cell Biology (2014) 16(9):909-17. [PDF]
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Regulation of cell adhesion and migration by cell-derived matrices
Kutys ML, Doyle AD, Yamada KM. Experimental Cell Research (2013) 319(16):2434-9. [PDF] |
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Dimensions in cell migration
Doyle AD, Petrie RJ, Kutys ML, Yamada KM. Current Opinion in Cell Biology (2013) 25(5):642-9. [PDF] |
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Ubiquitylation of phosphatidylinositol 4-phosphate 5-kinase type I γ by HECTD1 regulates focal adhesion dynamics and cell migration
Li X, Zhou Q, Sunkara M, Kutys ML, Wu Z, Rychahou P, Morris AJ, Zhu H, Evers BM, Huang C. Journal of Cell Science (2013) 126(12):2617-28. [PDF] |
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Micro-environmental control of cell migration--myosin IIA is required for efficient migration in fibrillar environments through control of cell adhesion dynamics
Doyle AD, Kutys ML, Conti MA, Matsumoto K, Adelstein RS, Yamada KM. Journal of Cell Science (2012) 125(9):2244-56. [PDF]
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Monte carlo analysis of neck linker extension in kinesin molecular motors
Kutys ML, Fricks J, Hancock WO. PLoS Computational Biology (2010) 6(11):e1000980. [PDF] |
